Faculty of Medicine, Dentistry and Health SciencesResearch Domains

Biosciences Domain / Infection and Immunity Domain - Combined Research andTechnology Forum

The Forum was held at the Bio21 Institute on July 16 and 17. See the program below.

The purpose of the Technology Forum was to showcase the expertise and technologies offered by our Faculty, the University and its associated institutes with a view to encouraging new collaborations and increased uptake of high-end technologies at a local level. Symposia included research stories based around successful use of proteomics, metabolomics, genomics, live imaging, protein-protein interactions, drug development and genetic screens.

There was also a Facility managers’ session outlining access to and the cost of using certain technologies.

The two day meeting included a dinner to bring together MDHS researchers with a research interest in Infection and Immunity and Biosciences.

Andy Hill
Coordinator Biosciences Domain
Contact: biosciences-research@unimelb.edu.au

Liz Hartland
Coordinator Infection and Immunity Domain
Contact: infection-research@unimelb.edu.au

 

 

 

 

 

 

 

 

 

 

 

Research and Technology Forum - Program

 

Day 1

 

Mass spectrometry, proteomics and metabolomics

Mediator: Andy Hill

1. Malcolm McConville (Biochemistry and Molecular Biology)
Metabolomics; applications to infection and immunity and beyond

Hear an interview with Malcolm

2. Tony Purcell (Biochemistry and Molecular Biology)
Immunoproteomics: defining the targets of the immune response

Hear an interview with Tony

3. Mike Hubbard (Pharmacology)
Proteomics and PMV

Associate Professor Andrew Hill

 

Hear Andy talk about the first day of the forum

 

Cell imaging and analyses

Mediator: Liz Hartland

1. Matthew Burton (Murdoch Children’s Research Institute)
Fluorescence Activated Chromosome Sorting

Hear an interview with Matthew

2. Paul Gleeson (Biochemistry and Molecular Biology)
High resolution confocal imaging

Hear an interview with Paul

3. Sarah Ellis (Peter MacCallum Cancer Centre)
The use of Immuno-Electron Microscopy to Investigate the Hemopoietic Stem Cell Niche in situ: A novel triple immuno-gold technique

Hear an interview with Sarah

Dr Elizabeth Hartland

 

Hear Liz talk about the first day of the forum

 

Genomics and bioinformatics

Mediator: Andy Hill

1. Alex Andrianopoulos (Genetics)
Genomic studies of fungal pathogenesis and Development

2. Vladimir Likic (Bio21 Institute)
Systems biology & bioinformatics

3. Jan Schreoder (School of Computer Science and Software Engineering and NICTA) Bioinformatics

Hear an interview with Jan

Audience members

 

Live imaging and analysis

Mediator: Liz Hartland

1. Heather Young (Anatomy and cell biology)
Live fluorescent imaging: Pitfalls and use of photoconvertible fluorescent proteins
to analyze cell migration

2. Damian Myers (Medicine)
Live fluorescence imaging

3. Odilia Wijburg (Microbiology and Immunology)
Use of in vivo bioluminescent imaging to study synergism between Streptococcus pneumoniae and influenza A virus

Hear an interview with Odilia

Dr Odilia Wijburg

 

Day 2

Hear Andy Hill talk about the second day of the forum

Protein-protein interactions and biophysics

Mediator: Liz Hartland

1. Andrew Brooks (Microbiology and Immunology)
Recognition of non classical MHC class I molecules by the innate and adaptive immune system

2. Matt Perugini (Biochemistry and Molecular Biology)
Quantitating Macromolecular Interactions by Analytical Ultracentrifugation

3. Andrew Clayton (Ludwig Institute)
Mapping protein-protein interactions in the cell using fluorescence lifetime imaging microscopy

David Pejoski and Florienne Loder

 

Structural Biology, Drug Discovery and Development

Mediator: Andy Hill

1. Gary Anderson (Pharmacology)
New drugs: from bench to market

2. Paul Gooley (Biochemistry and Molecular Biology)
NMR

3. Michael Parker (St Vincent’s Institute)
Structure-based drug design using computers, NMR and crystallography

4. Tony Hughes (Pharmacology)
Medicinal chemistry and drug screening

Dr Kaylene Simpson

 

Functional genomics and genetic screens

Mediator: Liz Hartland

1. Gordon Smyth (WEHI)
Statistical analysis of microarray expression data throws light on the
immunological profile of early multiple sclerosis

2. Warren Alexander (WEHI)
Genome wide ENU mutagenesis screens for blood cell
Phenotypes

3. Kaylene Simpson (Peter Mac)
Strategies for genome scale RNAi screens

Hear an interview with Kaylene

Professor Gordon Smyth

 

Technology Managers Session

Mediator: Andy Hill

1. Simon Crawford (Department of Botany, UoM)
Immuno-electron microscopy at the School of Botany

2. Ken Goldie (Bio21 Institute)
Electron Microscopy at Bio21

3. David Keizer (Bio21 Institute)
NMR Facility at Bio21

To find out more about Bio21 NMR visit our website:
www.bio21.org/platform-technologies/nmr-facility

4. Nick Williamson (Bio21 Institute)
Mass Spectrometry and the Research Transfer Facility at Bio21

5. Benjamin Ong (Murdoch Childrens Research Institute)
Overview of Sequenom Platform and its Applications

6. Melissa Southey (Department of Pathology)
Managing and mobilizing our research bioresources – The MDHS Biorepository Facility

7. John Furness (Department of Anatomy and Cell Biology)
The Australian Phenomics Network (APN)

Associate Professor Melissa Southey

 

Associate Professor Ian van Driel and Professor John Furness

 

CLOSING REMARKS AND DRINKS

Associate Dean Research Jim McCluskey

Hear an interview with Jim

 

 


Professor Jim McCluskey

Hear the Tech Forum's organisers Andy Hill and Liz Hartland talk about the outcomes of the forum
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